Figure 1
Serum concentrations of ANGP-1 and ANGP-2 in the 32 patients with PH, 60 age-matched HC, and 75 patients with IPF without PH. The serum ANGP-1 concentration in patients with PH tended to be higher but was not significantly higher compared with that in age-matched HC (a median, 40.6 ng/mL vs. 31.9 ng/mL [p = 0.179], respectively). The serum ANGP-1 concentration in patients with PH was significantly higher than that in patients with IPF without PH (a median, 40.6 ng/mL vs. 19.6 ng/mL [p < 0.001], respectively). The serum ANGP-2 concentration in patients with PH was significantly higher compared with that in age-matched HC or that in patients with IPF without PH (b median, 2.48 ng/mL vs. 2.01 ng/mL [p = 0.025] and 1.88 ng/mL [p = 0.008], respectively). ANGP angiopoietin, PH pulmonary hypertension, IPF idiopathic pulmonary fibrosis, HC healthy controls.
