Figure 5

Survival curves from ANGP measurement. Thirty-one patients with PH, who were followed up, were divided into two groups according to the median serum ANGP-1 and ANGP-2 concentrations: the ANGP-1 high group (≥ 40.62 ng/mL), the ANGP-1 low group (< 40.62 ng/mL), the ANGP-2 high group (≥ 2.48 ng/mL), and the ANGP-2 low group (< 2.48 ng/mL). Kaplan–Meier curves of survival probability from the time of ANGP measurement are shown. Patients with a high ANGP-2 concentration had significantly poorer survival compared with those with a low ANGP-2 concentration (b log-rank, p = 0.022). The 2-year survival rate was 44.7% in the ANGP-2 high group and 92.9% in the ANGP-2 low group (b). Significant difference was not observed between patients with high and low ANGP-1 concentrations (a; p = 0.407). ANGP angiopoietin, PH pulmonary hypertension.