Figure 1

Exercise-induced JNK phosphorylation is load-dependent, while mTOR and p70S6K phosphorylation is muscle-type dependent. Specific phosphorylation (phosphorylated protein / total protein) of Y397-FAK (a), pS2448-mTOR (b), pT421/S424-p70S6K (c), and pT183/Y185-JNK (d) as measured in 33 µg soluble protein from exercised and contralateral control TA and EDL muscles after a 28-min exercise stimulus with a high or a low load. Post-hoc significant differences denoted with *, ** p < 0.05 and 0.01 versus control leg; + , ++ p < 0.05 and 0.01 vs EDL within same exercise group; $$ p < 0.01 versus low load exercised group within the same muscle. Data are presented as individual muscle values (circles), contralateral comparisons (lines) and group means (bars) (n = 8 per group).