Figure 3
From: Multiwell Raman plate reader for high-throughput biochemical screening

High-throughput ATRaS for the identification of the inhibitor binding site in a protein. (a) Schematic of SERS-ATRaS with the developed Raman plate reader. (b) Raman spectra of 192 fractions observed at 3 s. (c) Raman peak height at 1980 cm−1 (green) and UV absorbance at 215 nm (black) for each fraction. (d) Mass spectrum observed at fraction #137. The MS spectrum is good agreement with that of alt-AOMK labeled peptide, containing the amino-acid sequence of 19EIRDQGSCGSCWAFGAVEAISDR41, as reported in Ref.18.