Table 2 Risk of subsequent liver and intrahepatic cancer in non-HP infected PPU patients with simple suture and TVP.

From: Decreased risk of liver and intrahepatic cancer in non-H. pylori-infected perforated peptic ulcer patients with truncal vagotomy: a nationwide study

 

Simple suture

TVP

TVP versus simple suture

Propensity score matching

TVP versus simple suture

Simple suture

TVP

Case

Rate

Case

Rate

HR (95% CI)†

Case

Rate

Case

Rate

HR (95% CI)

Overall

675

2.11

54

0.99

0.71 (0.54–0.95)*

77

1.45

54

1.00

0.69 (0.49–0.97)*

Gender

Women

168

1.79

6

0.65

0.53 (0.23–1.21)

7

0.74

6

0.65

0.88 (0.30–2.63)

Men

507

2.25

48

1.06

0.74 (0.55–1.01)

70

1.60

48

1.07

0.67 (0.46–0.96)*

Age, years

20–44

48

0.68

12

0.49

1.14 (0.58–2.25)

10

0.42

12

0.50

1.19 (0.51–2.74)

45–64

278

2.29

24

1.20

0.68 (0.44–1.04)

38

2.04

24

1.20

0.59 (0.35–0.98)*

65+

349

2.73

18

1.80

0.70 (0.43–1.11)

29

2.75

18

1.80

0.66 (0.36–1.18)

Comorbidity

No

205

1.23

32

0.70

0.71 (0.49–1.04)

54

1.21

32

0.70

0.57 (0.37–0.89)*

Yes

470

3.09

22

2.58

0.78 (0.51–1.20)

23

2.62

22

2.58

0.99 (0.55–1.78)

  1. Rate, per 1000 person-years.
  2. HR hazard ratio, CI confidence interval, HP helicobacter pylori, PPU perforated peptic ulcer, TVP truncal vagotomy and pyloroplasty.
  3. †Multivariable model, adjusted for age, gender, diabetes, cirrhosis, hypertension, hyperlipidemia, and stroke.
  4. *p < 0.05.
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