Table 3 Association between serum uric acid and lumbar bone mineral density among 6704 US adult males, weighted.

From: No association between serum uric acid and lumbar spine bone mineral density in US adult males: a cross sectional study

 

Model 1

Model 2

Model 3

Model 4

β (95% CI)

β (95% CI)

β (95% CI)

β (95% CI)

SUA per 1 mg/dL increase

− 0.002 (− 0.006, 0.002)

− 0.002 (− 0.006, 0.002)

− 0.003 (− 0.007, 0.002)

− 0.002 (− 0.007, 0.002)

SUA clinical cutoffs

 < 7 mg/dL

Ref

Ref

Ref

Ref

≥ 7 mg/dL

− 0.004 (− 0.015, 0.008)

− 0.005 (− 0.016, 0.007)

− 0.006 (− 0.018, 0.006)

− 0.006 (− 0.018, 0.007)

SUA (quartile)

Q1

Ref

Ref

Ref

Ref

Q2

− 0.007 (− 0.021, 0.007)

− 0.007 (− 0.021, 0.006)

− 0.006 (− 0.020, 0.008)

− 0.006 (− 0.020, 0.009)

Q3

− 0.004 (− 0.021, 0.013)

− 0.005 (− 0.022, 0.012)

− 0.004 (− 0.020, 0.013)

− 0.004 (− 0.021, 0.013)

Q4

− 0.004 (− 0.018, 0.011)

− 0.005 (− 0.020, 0.009)

− 0.005 (− 0.020, 0.010)

− 0.004 (− 0.020, 0.011)

P for trend

0.774

0.605

0.650

0.696

  1. Model 1 was adjusted for none. Model 2 was adjusted for age, race/ethnicity, education, physical activity, smoking and drinking. Model 3 was adjusted for all covariables in model 2 plus body mass index (BMI), calcium supplementation, energy intake, protein intake, serum calcium, serum phosphorus, 25-OH-D (1,25,D), parathyroid hormone, serum alkaline phosphatase (ALP), C-reactive protein (CRP), serum albumin and estimated glomerular filtration rate (eGFR). Model 4 was adjusted for age, race/ethnicity, smoking, BMI, serum albumin, eGFR, CRP, serum calcium, 1,25,D and calcium supplementation. The adjusted variables in model 4 were determined based on the change in effect of more than 10% when added to this model.
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