Table 4 Subgroup analyses of the association of serum uric acid with lumbar bone mineral density, weighted.

From: No association between serum uric acid and lumbar spine bone mineral density in US adult males: a cross sectional study

Characteristics

N, unweighted

Lumber spine BMD

P-value

P for interaction

β (95%CI)

Age, years

   

0.53

 < 40

3475

− 0.005 (− 0.011, 0.001)

0.109

 

≥ 40, < 60

1956

0.001 (− 0.006, 0.008)

0.781

 

≥ 60

1273

− 0.004 (− 0.013, 0.006)

0.452

 

Race/Ethnicity

   

0.75

Non‐Hispanic White

3032

− 0.003 (− 0.008, 0.003)

0.384

 

Non‐Hispanic Black

1436

0.002 (− 0.005, 0.009)

0.572

 

Mexican American

1708

− 0.004 (− 0.011, 0.003)

0.279

 

Other race

528

− 0.006 (− 0.019, 0.007)

0.371

 

Education

   

0.76

 < High school

2186

− 0.003 (− 0.009, 0.003)

0.256

 

High school

1653

− 0.002 (− 0.009, 0.005)

0.662

 

 > High school

2856

− 0.004 (− 0.009, 0.002)

0.203

 

Physical activity

   

0.16

Sedentary

1194

− 0.006 (− 0.014, 0.002)

0.115

 

Low

1586

0.001 (− 0.006, 0.008)

0.804

 

Moderate

1058

0.004 (− 0.006, 0.013)

0.431

 

High

2173

− 0.006 (− 0.012, 0.000)

0.048

 

Smoker

   

0.59

Never

2530

− 0.003 (− 0.009, 0.003)

0.299

 

Ever

1514

0.002 (− 0.005, 0.009)

0.657

 

Current

1698

− 0.007 (− 0.014, 0.000)

0.055

 

Drinker

   

0.54

No

4002

− 0.002 (− 0.007, 0.002)

0.315

 

Yes

2408

− 0.001 (− 0.006, 0.005)

0.829

 

BMI, kg/m2

   

0.39

 < 24

1887

− 0.005 (− 0.012, 0.002)

0.149

 

≥ 24, < 28

2208

0.000 (− 0.006, 0.006)

0.959

 

≥ 28

2609

− 0.002 (− 0.007, 0.003)

0.492

 

eGFR, mL/min/1.73 m2

   

0.21

 < 90

1072

− 0.005 (− 0.013, 0.004)

0.235

 

≥ 90, < 120

3855

− 0.003 (− 0.008, 0.001)

0.149

 

≥ 120

1777

0.004 (− 0.003, 0.010)

0.269

 

Survey years

   

0.64

1999–2000

1595

− 0.002 (− 0.010, 0.005)

0.548

 

2001–2002

1781

0.001 (− 0.006, 0.008)

0.847

 

2003–2004

1742

− 0.003 (− 0.010, 0.002)

0.174

 

2005–2006

1586

− 0.003 (− 0.010, 0.004)

0.428

 
  1. The model was adjusted for age, race/ethnicity, education, physical activity, smoking, drinking, body mass index, calcium supplementation, energy intake, protein intake, serum calcium, serum phosphorus, 25-OH-D, parathyroid hormone (PTH) serum alkaline phosphatase (ALP), C-reactive protein (CRP), serum albumin and estimated glomerular filtration rate except the corresponding stratification variable.
  2. Serum ALP, PTH and CRP were log2 transformed prior to regression analysis.
Back to article page