Table 1 Description of general characteristics, Disease features, and treatments of RA patients overall and stratified by gender.

From: Plasma expression of microRNA-425-5p and microRNA-451a as biomarkers of cardiovascular disease in rheumatoid arthritis patients

 

RA (n = 214)

Female (n = 138)

Male (n = 76)

P

Characteristics of the groups

Gender-female (%, n)

64.5 (138)

   

Age (years, SD)

58(12)

57 (12)

59 (12)

0.55

Body mass index (kg/m2, SD)

27.8 (5.9)

27.7 (6.6)

28.1 (4.4)

0.62

Waist circumference (cm, SD)

93 (15)

88 (15)

100 (12)

 < 0.001

SBP (mmHg, SD)

137 (21)

135 (21)

142 (21)

0.024

DBP (mmHg, SD)

81 (12)

80 (13)

84 (12)

0.025

LDL cholesterol (mg/dL, SD)

119 (31)

118 (31)

120 (31)

0.75

HDL cholesterol (mg/dL, SD)

66 (19)

72 (18)

54 (15)

 < 0.001

Triglycerides (mg/dL, SD)

105 (55)

102 (54)

112 (58)

0.21

Glucose (mg/dL, SD)

95 (23)

94 (25)

96 (18)

0.35

Current smoker (%, n)

26.2(56)

27.5(38)

23.7(18)

0.34

Hypertension (%, n)

60.3 (129)

53 (73)

74 (56)

0.003

Diabetes mellitus (%, n)

11.7 (25)

10.9 (15)

13.2 (10)

0.62

Dyslipidaemia (%, n)

41.1(88)

39.1 (54)

44.7 (34)

0.425

Disease features

Disease onset (years, SD)

9.4 (9.1)

10.1 (9.9)

8.2 (7.5)

0.12

DAS28 (%, n)

3.5 (1.3)

3.7 (1.3)

2.98 (1.1)

 < 0.001

 Remission (%, n)

27.1 (58)

20.3 (28)

39.5 (30)

 < 0.001

 Low activity (%, n)

18.7 (40)

14.5 (20)

26.3 (20)

 

 Moderate activity (%, n)

44.4 (95)

52.2 (72)

30.3 (23)

 

 High activity (%, n)

9.8 (21)

13 (18)

3.9 (3)

 

HAQ (mean, SD)

0.45 (0.52)

0.59 (0.56)

0.21 (0.34)

 < 0.001

Rheumatoid factor + (%, n)

72.4 (155)

71.7 (99)

73.7 (56)

0.76

ACPA + (%, n)

81.3 (174)

83.3 (115)

77.6 (59)

0.31

ESR (mm/h, SD)

37 (26)

40 (27)

32 (22)

0.019

CRP (mg/dL, SD)

0.72 (0.83)

0.73 (0.80)

0.70 (0.88)

0.83

Fibrinogen (mg/dL, SD)

443 (97)

442 (96)

444 (100)

0.91

Treatments (%, n)

DMARDs

75.2 (161)

71.7 (99)

81.6 (62)

0.11

Biological agent

20.1 (43)

23.2 (32)

14.5 (11)

0.13

NSAIDs

57 (122)

57.2 (79)

56.6 (43)

0.92

Corticosteroids

50.9 (109)

53 (73)

47 (36)

0.44

  1. n = number of individuals, SBP = systolic blood pressure, DBP = diastolic blood pressure, HAQ = health assessment questionnaire index, ACPA = citrullinated anti-cyclic peptide antibodies, ESR = erythrocyte sedimentation rate, CRP = C-reactive protein, DAS28 = disease activity score, DMARDs = disease-modifying antirheumatic drugs, NSAIDs = non-steroidal anti-inflammatory drugs, SD = standard deviation, p = p value.
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