Table 2 Adjusted OR estimates of the effect of miR-425-5p and miR-451 expression on pathological cIMT (A) and on prior CVD (B).

From: Plasma expression of microRNA-425-5p and microRNA-451a as biomarkers of cardiovascular disease in rheumatoid arthritis patients

 

OR

P

R2 (%)

AIC

A. Pat-cIMT

Model 1

  

22

129.52

Model 1 + miR-451

0.088

0.017

28

126.33

Model 2

  

29

70.23

Model 2 + miR-425-5p

4.95

0.06

39

67.87

B. Prior CVD

Model 3

  

42

54.43

Model 3 + miR-425-5p

17.06

0.026

53

49.4

  1. Adjusted OR estimates were assessed by logistic regression analysis applied to women (model 1) and to men (model 2 and 3) with or without inclusion of candidate miRs expression. Models were initially adjusted for age, RA disease onset, BMI, ischemic heart disease, peripheral artery disease, ictus, creatinine, and treatments. OR = odds ratio, AIC = Akaike information criteria. p = p value.
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