Table 4 Disease-related variables and variables characteristics of the population studied associated with the expression levels of miR-425-5p and miR-451 stratified by sex.

From: Plasma expression of microRNA-425-5p and microRNA-451a as biomarkers of cardiovascular disease in rheumatoid arthritis patients

 

DCt-425

DCt-425

r

β

p

r

β

p

Men

Disease duration

0.092

0.006

0.434

0.06

0.004

0.609

HAQ

 − 0.022

 − 0.031

0.853

 − 0.001

 − 0.001

0.993

DAS28

 − 0.134

 − 0.06

0.255

0.284

0.120

0.014

ESR

 − 0.244

 − 0.005

0.036

0.385

0.008

0.001

CRP

 − 0.156

 − 0.085

0.185

0.148

0.077

0.208

Fibrinogen

 − 0.150

 − 0.001

0.203

0.435

0.002

0.0001

Age

 − 0.56

 − 0.002

0.635

0.0076

0.003

0.52

BMI

0.002

0.0001

0.984

0.194

0.02

0.097

SBP

0.076

0.002

0.521

0.146

0.003

0.216

DBP

0.028

0.001

0.810

0.069

0.003

0.558

Glucose

0.024

0.001

0.840

0.016

0.0001

0.891

HbA1c (%)

 − 0.081

 − 0.064

0.497

 − 0.01

 − 0.008

0.932

Women

Disease duration

0.091

0.004

0.29

0.036

0.001

0.680

HAQ

0.109

0.086

0.203

0.127

0.096

0.138

DAS28

0.107

0.035

0.215

0.163

0.051

0.056

ESR

 − 0.091

 − 0.001

0.290

0.161

0.002

0.06

CRP

 − 0.038

 − 0.02

0.662

0.147

0.075

0.087

Fibrinogen

 − 0.041

0.0001

0.630

0.175

0.001

0.041

Age

 − 0.045

 − 0.002

0.602

0.049

0.002

0.566

BMI

0.008

0.001

0.922

0.04

0.002

0.643

SBP

 − 0.118

 − 0.002

0.168

 − 0.043

 − 0.001

0.613

DBP

 − 0.056

 − 0.002

0.514

0.668

0.002

0.431

Glucose

0.082

0.001

0.328

0.084

0.001

0.331

HbA1c (%)

0.059

0.027

0.493

0.089

0.038

0.303

  1. SBP = systolic blood pressure, DBP = diastolic blood pressure, HAQ = health assessment questionnaire index, ESR = erythrocyte sedimentation rate, CRP = C-reactive protein, DAS28 = disease activity score, BMI = Body mass index, HbA1c = Glycated haemoglobin. r = Pearson’s coefficient, p = p value, β = linear regression estimates.
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