Figure 4
Digital subtraction indocyanine green angiography in which segmented pattern can be seen (same eye as Fig. 2). (A) We could define segment (functional lobule) as an area of fast flow surrounded by a perimeter of slow flow. The dye front appears first in the centre of each segmented unit and spread towards the perimeter of each unit in the macular region. In the next frame (0.2 s later), the central area becomes dark (B), which implies no change in fluorescence as compared with previous frame. The location of unit correlate well in the two images. The zones between adjacent segmented units appeared faintly brighter in (B) compared to in (A), which suggests a slow movement of the dye front in this region. Note that the organization of these zones is not regular in relation to the adjacent units. There was also a range of width, estimated between 50 and 200 µm. (C) Registration of (A—in red) and (B—in blue) highlighted the neighbouring units (functional lobules) which can be seen as red areas (fast flow) separated blue areas (slow flow).
