Figure 9 | Scientific Reports

Figure 9

From: Novel Tl(III) complexes containing pyridine-2,6-dicarboxylate derivatives with selective anticancer activity through inducing mitochondria-mediated apoptosis in A375 cells

Figure 9The alternative text for this image may have been generated using AI.

Effect of complexes on the apoptosis protein levels in A375 cells for 24 h. (a) Western blot analysis of p53, Bcl − 2, Bcl − xl, Bax, Bad, Bim, and Cyt-c levels after complex treatment. β − actin was used as an internal control. The blots were cropped before hybridization with antibodies during blotting. (b) Densitometric analysis of the expression of p53, Bcl − 2, Bcl − xl, Bax, Bad, Bim, and Cyt-c. The percentage values are those relative to the control. Results are the mean ± S.E.M (n = 3) *p < 0.05, **p < 0.01, ***p < 0.001.

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