Table 1 Protein quantification in 4 cell lines. Summary of the number of quantified proteins from biological triplicate analysis of each cell line in cellular proteome or secretome.

From: A proteomic platform to identify off-target proteins associated with therapeutic modalities that induce protein degradation or gene silencing

 

Cell lines

Quantified proteins (gene centric, 1% FDR)

# of cell-type enriched proteins (gene centric, ≥ 2FC, 1% FDR)

Peptides (unique, 1% FDR)

Peptides/protein (unique, median)

Sequence coverage (%)/protein (unique, mean)

Total quantified proteins (gene centric, 1% FDR)

Cellular proteome

COR-L24

8712

819

173,705

11

36

10,466

KYSE-270

8459

249

SU8686

8126

311

TT

8290

526

Secretome

COR-L24

2117

242

35,230

7

29

3139

KYSE-270

2000

193

SU8686

2068

294

TT

1675

242