Table 3 Parameters of blood clot contraction in the COVID-19 patients.
From: Altered platelet and coagulation function in moderate-to-severe COVID-19
Comparison groups and subgroups | Parameters of blood clot contraction | |||
|---|---|---|---|---|
Extent of clot contraction, % | Lag time, sec | Area under the curve, a.u | Average velocity, %/s × 10–3 | |
(a) Patients with COVID-19 and healthy donors | ||||
Patients with COVID-19 (n = 215) | 41 (37; 43)*** | 180 (150; 213)*** | 315 (261; 354)*** | 34 (31; 36)*** |
Healthy subjects (n = 40) | 48 (43; 52) | 75 (45; 120) | 380 (316; 447) | 38 (35; 42) |
(b) Dependence on the severity of the disease | ||||
Moderate severity (n = 149) | 41 (38; 44)* | 180 (150; 195)** | 322 (280; 358)** | 34 (32; 36)* |
Severe (n = 51) | 39 (33; 43) | 210 (165; 255) | 298 (220; 337) | 32 (27; 35) |
(c) Dependence on the outcome of the disease | ||||
Favorable (n = 184) | 41 (38; 44)* | 180 (150; 210)*** | 317 (271; 357)** | 34 (31; 36)** |
Fatal (n = 16) | 35 (27; 42) | 255 (195; 349) | 238 (156; 320) | 30 (22; 35) |
(d) Dependence on the presence of concomitant hematologic neoplasms | ||||
Neoplasms (n = 8) | 28 (17; 42)* | 218 (150; 251) | 200 (117;304)** | 23 (14; 34) |
No neoplasms (n = 207) | 41 (37; 44) | 180 (150; 210) | 316 (270; 357) | 34 (31; 36) |
(e) Dependence on the presence of concomitant coronary heart disease | ||||
Coronary heart disease (n = 41) | 39 (33; 41)** | 195 (165; 240)* | 298 (227; 335)* | 32 (29; 35)* |
No coronary heart disease (n = 159) | 41 (38; 44) | 180 (150; 210) | 324 (276; 361) | 34 (32; 36) |
(f) Dependence on the presence of concomitant ischemic stroke or transient ischemic attacks | ||||
Ischemic stroke or transient ischemic attacks (n = 23) | 36 (27; 43)* | 225 (165; 285)** | 272 (152; 318)* | 30 (22; 36)* |
No ischemic stroke or transient ischemic attacks (n = 162) | 41 (38; 44) | 180 (150; 210) | 323 (279; 358) | 34 (31; 36) |
(g) Dependence on the gender | ||||
Women (n = 115) | 42 (39; 45)*** | 180 (150; 225) | 323 (291; 371)** | 34 (32; 37)*** |
Men (n = 100) | 39 (35; 42) | 180 (150; 210) | 306 (253; 341) | 33 (29; 35) |
