Figure 2 | Scientific Reports

Figure 2

From: Identification of Maturity-Onset-Diabetes of the Young (MODY) mutations in a country where diabetes is endemic

Figure 2

(A) Represents pedigree of a family positive for Maturity Onset Diabetes of the Young (MODY3). The square symbol represents male, and the circle represents female. The filled in symbols indicate affected individuals and the blue arrow indicates the index case. (B) Exome sequencing summary layout depicting part of the HNF1A gene location on chromosome 12 at the top and the exons coverage in green and blue. The location of the c.872dupC, (p.Gly292fs) frameshift mutation is represented by a vertical yellow bar and the reference sequence and the altered codon is highlighted. (C) Chromatogram represents Sanger sequencing of the HNF1A gene in control family member (top) and confirming the heterozygous frameshift mutation in the index (bottom arrow-line).

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