Table 1 Demographic data of subjects.

From: Relationship between total cholesterol level and tuberculosis risk in a nationwide longitudinal cohort

 

Total (N = 5,000,566)

Patients who did not develop TB (n = 4,968,488)

Patients who developed TB (n = 32,078)

p value

Age, years

47.2 ± 14.1

47.1 ± 14.1

56.1 ± 15.8

< 0.001

Sex, male

2,732,571 (54.7)

2,713,664 (54.6)

18,907 (58.9)

< 0.001

Body mass index, kg/m2

23.7 ± 3.2

23.7 ± 3.2

22.6 ± 3.1

< 0.001

Smoking status

 Never

2,983,062 (59.7)

2,964,482 (59.7)

18,580 (57.9)

< 0.001

 Ex

712,535 (14.2)

707,910 (14.3)

4625 (14.4)

 

 Current

1,304,969 (26.1)

129,6097 (26.1)

8872 (27.7)

 

Low income

1,075,880 (21.5)

78.5 (21.5)

78.0 (22.0)

0.026

Alcohol consumption

 No

2,585,695 (51.7)

2,567,446 (51.7)

18,249 (56.9)

< 0.001

 Mild

2,020,311 (40.4)

2,009,501 (40.4)

10,810 (33.7)

 

 Heavy

394,560 (7.9)

391,542 (7.9)

3018 (9.4)

 

Comorbid conditions

 Diabetes mellitus

436,055 (8.7)

430,767 (8.7)

5049 (15.7)

< 0.001

 Hypertension

1,350,494 (27.0)

1,338,510 (26.9)

11,904 (37.1)

< 0.001

 Dyslipidemia

909,576 (18.2)

903,271 (18.2)

6152 (19.2)

< 0.001

 Heart disease

99,770 (3.2)

156,010 (3.1)

1703 (5.3)

< 0.001

 Stroke

51,644 (1.6)

80,986 (1.6)

741 (2.3)

< 0.001

 Chronic kidney disease, GFR < 30 mL/min/1.73 m2

72,882 (1.5)

72,363(1.5)

519 (1.6)

< 0.001

 Asthma or COPD

416,492 (8.3)

411,887 (8.3)

4689 (14.6)

< 0.001

Regular physical activity

907,094 (18.1)

901,780 (18.2)

5533 (17.3)

< 0.001

Lipid profile

 Total cholesterol level, mg/dL

195.1 ± 36.8

195.1 ± 36.8

191.0 ± 37.9

< 0.001

 LDL cholesterol, mg/dL

113.2 ± 33.9

113.2 ± 33.9

109.9 ± 34.8

< 0.001

 Triglycerides, mg/dL

112.2 (112.2–112.3)

112.2 (112.2–112.3)

110.7 (110.1–111.4)

< 0.001

 HDL cholesterol, mg/dL

55.2 ± 17.3

55.2 ± 17.2

55.4 ± 21.5

< 0.001

Statin use

381,229 (7.6)

378,101 (7.6)

3153 (9.8)

< 0.001

  1. Data are presented as mean ± standard deviation or median (interquartile range) for continuous variables and number (%) for categorical variables.
  2. TB tuberculosis, GFR glomerular filtration rate, HDL high-density lipoprotein, LDL low-density lipoprotein.