Table 3 Human observer study results—smallest detected sphere size (in mm) for each scanner type, reconstruction algorithm and emission time.
From: Silicon-photomultiplier-based PET/CT reduces the minimum detectable activity of iodine-124
Sphere activity concentration (kBq/ml) | Scanner | OSEM | OSEM-TOF | OSEM-TOF+PSF | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
30 min | 16 min | 8 min | 4 min | 30 min | 16 min | 8 min | 4 min | 30 min | 16 min | 8 min | 4 min | ||
24.99 | Vision | 4.8 | 4.8 | 6.5 | 6.5 | 3.7 | 3.7 | 4.8 | 4.8 | 3.7 | 3.7 | 4.8 | 4.8 |
24.85 | mCT | 4.8 | 4.8 | 6.5 | 7.7 | 4.8 | 4.8 | 6.5 | 6.5 | 4.8 | 4.8 | 4.8 | 6.5 |
15.72 | Vision | 4.8 | 6.5 | 6.5 | 6.5 | 3.7 | 4.8 | 4.8 | 4.8 | 3.7 | 4.8 | 4.8 | 4.8 |
15.63 | mCT | 6.5 | 6.5 | 6.5 | 7.7 | 4.8 | 6.5 | 6.5 | 7.7 | 4.8 | 4.8 | 6.5 | 6.5 |
8.17 | Vision | 6.5 | 6.5 | 6.5 | 7.7 | 4.8 | 6.5 | 6.5 | 6.5 | 4.8 | 4.8 | 4.8 | 4.8 |
8.13 | mCT | 6.5 | 7.7 | 9.7 | 9.7 | 6.5 | 6.5 | 7.7 | 7.7 | 4.8 | 4.8 | 6.5 | 7.7 |
4.83 | Vision | 4.8 | 6.5 | 7.7 | 8.9 | 3.7 | 4.8 | 6.5 | 7.7 | 3.7 | 4.8 | 6.5 | 6.5 |
4.93 | mCT | 6.5 | 7.7 | – | – | 6.5 | 6.5 | 8.9 | – | 6.5 | 6.5 | 6.5 | 8.9 |
2.53 | Vision | 6.5 | 7.7 | 8.9 | – | 6.5 | 6.5 | 6.5 | 7.7 | 4.8 | 6.5 | 6.5 | 6.5 |
2.51 | mCT | 7.7 | – | – | – | 7.7 | 8.9 | – | – | 6.5 | 6.5 | 7.7 | – |
1.37 | Vision | 8.9 | 9.7 | – | – | 6.5 | 6.5 | 7.7 | – | 4.8 | 6.5 | 7.7 | 7.7 |
1.54 | mCT | – | – | – | – | 8.9 | – | – | – | 6.5 | 6.5 | – | – |
0.80 | Vision | 8.9 | 9.7 | – | – | 6.5 | 6.5 | 7.7 | – | 6.5 | 6.5 | 6.5 | – |
0.79 | mCT | – | – | – | – | 7.7 | – | – | – | 6.5 | 7.7 | – | – |
0.43 | Vision | – | – | – | – | 7.7 | 8.9 | – | – | 6.5 | 7.7 | – | – |
0.48 | mCT | – | – | – | – | – | – | – | – | 8.9 | – | – | – |
0.26 | Vision | – | – | – | – | 8.9 | 8.9 | – | – | 8.9 | 8.9 | – | – |
0.25 | mCT | – | – | – | – | – | – | – | – | – | – | – | – |