Table 4 MDA-Ratios between the Vision and the mCT for each sphere size, reconstruction algorithm, and emission time.

From: Silicon-photomultiplier-based PET/CT reduces the minimum detectable activity of iodine-124

Sphere diameter (mm)

OSEM

OSEM-TOF

OSEM-TOF+PSF

All reconstructions

30-min

16-min

8-min

4-min

30-min

16-min

8-min

4-min

30-min

16-min

8-min

4-min

All emission times (mean ± SD)

3.7

4.8

0.84

0.93

0.32

0.50

0.33

0.48

0.56 ± 0.26

6.5

0.59

0.67

0.79

0.18

0.42

0.74

0.53

0.54

0.74

0.76

0.60 ± 0.19

7.7

0.56

0.54

0.59

0.47

0.09

0.38

0.45

0.35

0.58

0.45 ± 0.16

8.9

0.29

0.55

0.61

0.53

0.42

0.49

0.48 ± 0.12

9.7

0.42

0.63

0.65

0.36

0.49

0.51 ± 0.13

All spheres (mean ± SD)

0.66  ±  0.16

0.57  ± 0.25

0.65  ± 0.11

0.58  ±  0.10

0.25  ±  0.11

0.34  ±  0.22

0.55  ±  0.19

0.44  ±  0.08

0.33  ±  0

0.51  ±  0.05

0.54  ± 0.28

0.58  ± 0.13

0.52 ± 0.18

  1. No values are indicated, if the MDA was outside the range that can be evaluated within this investigation (< 0.26 kBq/ml or > 25 kBq/ml) for one or both examined PET/CT systems.