Figure 2
Pseudo-absorbance spectra. (a,b) mean pseudo-absorbance spectra obtained from lentiviral particles resuspended in PBS (LP-PBS) or artificial saliva (LP-AS), and their respective negative controls (PBS-control and AS-control). (c,d) overall pseudo-absorbance spectra upon complete evaporation of the aqueous content. The concentration in (a–d) was 4000 TU∙µL−1. The shadowed area highlights the wavelength range in which shape features were more informative for the FFNN analysis. (e) PLS-DA three-dimensional score plot of LP-PBS vs. PBS-control (three latent variables and captured variances: V1 = 0.70, V2 = 0.12, V3 = 0.03). (f) PLS-DA three-dimensional score plot of AS-PBS vs. AS-control (three latent variables and captured variances: V1 = 0.75, V2 = 0.10, V3 = 0.02).
