Table 1 Clinicopathological features of T4a CC patients grouped by tumor size: data are reported for the whole study series and for one-to-one propensity-score matched pairs.
From: Tumor size improves the accuracy of the prognostic prediction of T4a stage colon cancer
Characteristics | Whole study series | Matched pairs (Case–control Method) | ||||
|---|---|---|---|---|---|---|
SG(n = 286) | LG(n = 496) | P | SG(n = 286) | LG(n = 286) | P | |
Sex | 0.118 | 0.397 | ||||
Male/female | 171/115 | 268/228 | 171/115 | 161/125 | ||
Age at surgery (yr) | 0.648 | 0.485 | ||||
≥ 65/< 65 | 98/188 | 178/318 | 98/188 | 106/180 | ||
Mean age at surgery | 0.087 | 0.994 | ||||
Mean ± SD | 60.8 ± 11.1 | 59.3 ± 12.7 | 60.8 ± 11.1 | 60.8 ± 11.4 | ||
Tumor location | 0.003 | 0.448 | ||||
Right colon/left colon | 156/130 | 324/172 | 156/130 | 165/121 | ||
Histology | 0.006 | 0.260 | ||||
Low grade/high grade | 202/84 | 302/194 | 202/84 | 214/72 | ||
Lymphovascular invasion | 0.010 | 0.605 | ||||
Present/absent | 32/254 | 90/406 | 32/254 | 36/250 | ||
Number of lymph nodes retrieval | 0.001 | 0.144 | ||||
Mean ± SD | 15.1 ± 5.6 | 16.7 ± 7.5 | 15.1 ± 5.6 | 15.9 ± 7.2 | ||
lymph nodes retrieval | 0.472 | 0.288 | ||||
> 12/≤ 12 | 209/77 | 374/122 | 209/77 | 220/66 | ||
Lymph node metastasis | 0.167 | 0.520 | ||||
N0/N1/N2 | 193/67/26 | 354/89/53 | 193/67/26 | 198/57/31 | ||
CEA level | 0.787 | 0.556 | ||||
Elevated(≥ 5.0 ng/ml) / Normal(< 5.0 ng/ml) | 124/162 | 220/276 | 124/162 | 131/155 | ||
CA19-9 level | 0.003 | 0.406 | ||||
Elevated(≥ 37.0 U/ml)/Normal(< 37.0 U/ml) | 38/248 | 108/388 | 38/248 | 45/241 | ||
Surgical procedure | < 0.001 | 0.064 | ||||
Open/laparoscopic | 43/243 | 142/354 | 65/221 | 60/226 | ||
Postoperative chemotherapy | 74.1 | 78.4 | 0.170 | 0.138 | ||
Yes/no | 212/74 | 389/107 | 212/74 | 227/59 | ||
Postoperative complications | < 0.001 | 0.136 | ||||
Present/absent | 8/278 | 51/445 | 8/278 | 15/271 | ||
