Table 1 Summary of smoke exposure experiments for validation in this study.

From: Signaling pathway perturbation analysis for assessment of biological impact of cigarette smoke on lung cells

Experiments

Cigarette type

Sample code

Tar (mg/cig)

Nicotine (mg/cig)

Dilution times

Sampling time (hour) after exposure

Optimal concentration

Reference

3R4F

9.4

0.73

1/10, 1/30, 1/100, 1/300,1/500,1/1000

0

Transcriptomic profiling: reference versus commercial cigarette

Reference

3R4F_0

9.4

0.73

1/500

0

Reference

3R4F_4

9.4

0.73

1/500

4

Reference

3R4F_24

9.4

0.73

1/500

24

Commercial

CB8_0

8

0.8

1/500

0

Commercial

CB8_4

8

0.8

1/500

4

Commercial

CB8_24

8

0.8

1/500

24

Transcriptomic profiling: different tar/nicotine contents

Commercial

AB8_4

8

0.7

1/500

4

Commercial

AB12_4

12

1

1/500

4

Commercial

CB8_4

8

0.8

1/500

4

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