Figure 8

Multidimensional scaling plot of GM profiles (A) based on Sørensen-Dice dissimilarities and alpha-diversity summary based on observed species index (B). Analyses were based on 90,000 reads per sample on zOTUs aggregated to the species level. * difference in observed species p < 0.05. Week 10; WT n = 10, Apoe KO n = 11 and week 20; WT n = 24, Apoe KO n = 26.