Figure 1 | Scientific Reports

Figure 1

From: Effects of intravitreal injection of siRNA against caspase-2 on retinal and optic nerve degeneration in air blast induced ocular trauma

Figure 1

Experimental design for siCASP2 and siEGFP injection studies. (A) Timeline “post-blast” study. Bilateral siCASP2 or siEGFP control were intravitreally injection 5 h after the initial 2 × 15 psi blast wave, and injections repeated every 7 days until perfusion and tissue collection at 28 dpi. (B) Experimental groups for “post-blast” injection study. (C) Timeline for “pre-blast” study. Bilateral siCASP2 or siEGFP controls were intravitreally injected 48 h before the initial 2 × 15 psi blast exposure and injections repeated every 7 d until perfusion and tissue collection at 14 dpi. (D) Experimental groups for “pre-blast” study. (E) Measured endpoints and eyes analysed.

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