Figure 1

Modifications in patients with less than 5 years of disease duration. Differences in the grey matter mean diffusivity (a) and in volume (b) between patients from the MS1 group and HC. The colour gradient from yellow to red indicates the effect size ranges. The bottom figure shows the changes in MD (in yellow), volume (in blue) and their overlap (in green). The figure was generated using BrainPainter software50.