Table 2 Longitudinal association between the severity of periodontitis and incidence of Parkinson’s disease.
Variables | n | Events | Person-years | Incidence rate per 1000 person-years | Model 1 | Model 2 | Model 3 | Model 3 (3-year lag) | Model 3 (5-year lag) |
|---|---|---|---|---|---|---|---|---|---|
Periodontitis | |||||||||
No | 5,922,621 | 24,034 | 42,772,055.50 | 0.56191 | 1 (reference) | 1 (reference) | 1 (reference) | 1 (reference) | (reference) |
Yes | 903,063 | 4,245 | 6,532,573.13 | 0.64982 | 1.099 (1.064, 1.136) | 1.082 (1.047, 1.118) | 1.090 (1.06,1.121) | 1.103 (1.069,1.138) | 1.109 (1.068,1.151) |
Type of periodontitis | |||||||||
None | 5,922,621 | 24,034 | 42,772,055.50 | 0.56191 | 1 (reference) | 1 (reference) | 1 (reference) | 1 (reference) | 1 (reference) |
Mild | 660,675 | 3,331 | 4,771,056.49 | 0.69817 | 1.103 (1.063, 1.143) | 1.088 (1.049, 1.128) | 1.095 (1.063,1.128) | 1.102 (1.066,1.139) | 1.101 (1.059,1.263) |
Moderate | 212,612 | 803 | 1,545,323.43 | 0.51963 | 1.095 (1.021, 1.175) | 1.069 (0.997, 1.148) | 1.076 (1.005,1.153) | 1.127 (1.045,1.215) | 1.156 (1.059,1.263) |
Severe | 29,776 | 111 | 216,193.21 | 0.51343 | 1.026 (0.852, 1.237) | 0.999 (0.829, 1.204) | 0.987 (0.82,1.188) | 0.999 (0.813,1.228) | 1.088 (0.86,1.377) |
Visit one year after treatment of periodontitis | |||||||||
No periodontitis | 5,922,621 | 24,034 | 42,772,055.50 | 0.56191 | 1 (reference) | 1 (reference) | 1 (reference) | 1 (reference) | 1 (reference) |
No re-visit | 844,743 | 3,938 | 6,109,817.15 | 0.64454 | 1.094 (1.058, 1.132) | 1.078 (1.042, 1.115) | 1.078 (1.04,1.119) | 1.099 (1.055,1.144) | 1.119 (1.067,1.174) |
Re-visit | 58,320 | 307 | 422,755.98 | 0.72619 | 1.165 (1.041, 1.304) | 1.136 (1.015, 1.272) | 1.114 (1.062,1.146) | 1.108 (1.062,1.157) | 1.097 (1.042,1.154) |
