Figure 6 | Scientific Reports

Figure 6

From: Intrinsic activation of β-catenin signaling by CRISPR/Cas9-mediated exon skipping contributes to immune evasion in hepatocellular carcinoma

Figure 6

Immune evasion of mouse HCC cells with β-catenin signaling activation. (a) Schematic representation of in vitro T cell killing assays. (b,c) Two- and three-dimensional T cell killing assays of the 3H3-Ctnnb1Δex3 cells. The left and right panels show representative phase-contrast images and cell viability data, respectively. Error bars are the mean ± SD. P-values were calculated by Welch's t test. **P < 0.01; ***P < 0.001. (d) and (e) Three-dimensional T cell killing assays of the β-catenin-knockdown and cytokine-expressing 3H3-Ctnnb1Δex3 cells, respectively. Error bars are the mean ± SD.

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