Figure 3

Schematic overview of the interactions between the identified metabolites and the involved pathways in non-transformed or transformed state. Metabolites that were discriminative for both matrices are indicated with (a), whereas those that were only found colon cell lines are indicated with (b) or tissue matrix with (c). Metabolites that are regulated in an opposite direction of the identified pathway are indicated in red and metabolites with conflicting changes between cell line and tissue samples or without a particular state association are written in lighter fray and italic.