Figure 6 | Scientific Reports

Figure 6

From: Assessing the role of initial conditions in the local structural identifiability of large dynamic models

Figure 6

Identifiability signature of the pharmacokinetics model (\(M_5\)) for the experimental setup with \(x_3(0)=x_4(0)=0\). (Top) The three singular values beyond the gap suggest that the sensitivity matrix is rank deficient and so the model is not identifiable. (Bottom) Entries in the last 3 columns of the \({\varvec{V}}\) matrix, related to the 3 zero valued singular values. The nonzero entries suggest that parameters \(\{k_a, \beta _1, \beta _2\}\) are unidentifiable.

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