Table 1 Clinical characteristics of control and RA patients including the two RA subgroups.

From: Plasma fibrinogen, d-dimer, and fibrin degradation product as biomarkers of rheumatoid arthritis

 

RA (N = 105)

Control (N = 102)

Low activity RA (N = 52)

Active RA (N = 53)

Age (years)

55.26 ± 16.27

53.69 ± 14.95

53.28 ± 19.00

56.98 ± 13.64

Gender (F/M)

78/27

76/26

39/13

39/14

BMI (kg/m2)

25.2 ± 2.7

25.8 ± 3.2

25.5 ± 3.1

24.7 ± 2.3

CRP (mg/L)

19.48 (7.21–50.62)

1.9 (0.7–2.9)

10.95 (5.87–16.9)

30.30 (10.56–53.90)

ESR (mm/h)

43.0 (17–76)

5.61 (2.93–10.45)

28.0 (15–62)

57.0 (21–83)

RF (IU/mL)

171.56 (25.2–410.00)

5.02 (2.30–13.40)

131.83 (21.20–310.00)

275.29 (35.16–907.0)

Anti-CCP (U/mL)

273.6 (43.8–395.0)

11.1 (6.2–17.5)

251.3 (20.6–375.0)

306.8 (91.7–400.0)

WBC (109/L)

6.65 ± 3.02

6.09 ± 2.23

6.42 ± 2.82

6.88 ± 3.36

RBC (1012/L)

4.09 ± 0.64

4.64 ± 0.62

4.24 ± 0.51

3.93 ± 0.46

Hb (g/L)

118.48 ± 20.77

137.20 ± 18.28

123.12 ± 20.38

110.37 ± 17.95

PLT (109/L)

235.12 ± 82.71

202.63 ± 76.27

216.05 ± 84.98

248.87 ± 89.13

FIB (mg/dL)

370.40 ± 126.02

274.73 ± 73.39

315.58 ± 96.44

401.76 ± 122.10

d-dimer (µg/L)

2962.78 ± 1892.94

907.13 ± 545.65

2145.61 ± 975.12

4382.46 ± 1881.72

FDP (mg/L)

19.43 ± 12. 31

2.15 ± 1.03

5.17 ± 3.48

37.13 ± 13.44

  1. Patients in low activity group with a DAS 28-CRP score lower than 2.7; active patients with a DAS 28-CRP score of 2.7 and higher.
  2. DAS28-CRP Disease Activity Score in 28 joints based on C-reactive protein, F female, M male, BMI body mass index, CRP C-reactive protein, ESR erythrocyte sedimentation rate, RF rheumatoid factor, Anti-CCP anti-cyclic citrullinated peptide, WBC white blood cells, RBC red blood cells, Hb hemoglobin, PLT platelet, FIB fibrinogen, FDP fibrin degradation product.