Table 2 Comparison of clinical characteristics between RA patients and Control, and between the two RA subgroups.

From: Plasma fibrinogen, d-dimer, and fibrin degradation product as biomarkers of rheumatoid arthritis

 

P-value (RA vs. control)

P-value (low activity RA vs. active RA)

Age (years)

0.117

0.236

Gender (F/M)

0.971

0.868

BMI (kg/m2)

0.20

0.45

CRP (mg/L)

< 0.001

< 0.001

ESR (mm/h)

< 0.001

< 0.001

RF (IU/mL)

< 0.001

< 0.05

Anti-CCP (U/mL)

< 0.001

0.373

WBC (109/L)

0.139

0.480

RBC (1012/L)

< 0.001

< 0.01

Hb (g/L)

 < 0.001

< 0.05

PLT (109/L)

< 0.01

< 0.01

FIB (mg/dL)

< 0.001

< 0.001

d-dimer (µg/L)

< 0.001

< 0.001

FDP (mg/L)

< 0.01

< 0.001

  1. Patients in low activity group with a DAS 28-CRP score lower than 2.7; active patients with a DAS 28-CRP score of 2.7 and higher.
  2. DAS28-CRP Disease Activity Score in 28 joints based on C-reactive protein, F female, M male, BMI body mass index, CRP C-reactive protein, ESR erythrocyte sedimentation rate, RF rheumatoid factor, Anti-CCP anti-cyclic citrullinated peptide, WBC white blood cells, RBC red blood cells, Hb hemoglobin, PLT platelet, FIB fibrinogen, FDP fibrin degradation product.
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