Figure 4
From: Nitroalkene fatty acids modulate bile acid metabolism and lung function in obese asthma
Murine bile acids increase in obese mice with AAD, and NO2-OA treatment reduces endogenous bile acids in these mice. β-muricholic (βMCA) and tauro-β-muricholic acid (tβMCA) levels were measured in serum (A) and lung (B) from lean and obese mice with and without AAD and NO2-OA treatment using SID-LC-HRMS. Graphs show data for n = 4–12 per group and combined from four independent experiments. *p < 0.05, **p < 0.01.
