Figure 3

The profiles of HFA, ISA, and PAC. Results calculated from contacts placed in the SOZ and nSOZ are shown as box-and-whisker plots in which the median values at each group are displayed. (a) HFA amplitude of ictal-SOZ contacts achieved its maximum value and was significantly higher than that of interictal-SOZ contacts, preictal-SOZ contacts, and ictal-nSOZ contacts. (b) ISA oscillations of ictal-SOZ contacts achieved their maximum values and are significantly higher than those of interictal-SOZ contacts, preictal-SOZ contacts, and ictal-nSOZ contacts. (c) For PAC (i.e., ISA-HFA SIm), the SIm of the preictal-SOZ contacts achieves its maximum value and is significantly higher than that of interictal-SOZ contacts and ictal-SOZ contacts. Median values of each group are indicated as numerical values and the center mark on each box. *Corrected p < 0.05, ** corrected p < 0.01, Wilcoxon rank-sum test or Wilcoxon signed-rank test across contacts, nine multiple comparison at each group corrected by Bonferroni method.