Figure 6

Average receiver operating characteristic curves of the results, after stage classification. (a) Preictal vs. interictal, ictal vs. interictal, and ictal vs. preictal stages are classified using HFA amplitude, ISA, and PAC (i.e., ISA-HFA SIm) of the SOZ contacts or the nSOZ contacts. SOZ-PAC shows the highest performance between the preictal and interictal states, whereas SOZ-ISA has a higher potential to distinguish between the ictal and interictal states and between the ictal and preictal states. (b) On classifying SOZ and nSOZ using HFA, ISA, and PAC, we found that HFA has the maximum AUC in the interictal and preictal states. ISA performs best in the ictal states.