Figure 2

Evaluation of cardiac autonomic control through double pharmacological blockade with methylatropine and propranolol. The bars show the percentage fluctuation of heart rate (HR) and intrinsic heart rate (IHR) after the administration of methylatropine (solid box) and propranolol (cross-hatched box) in vehicle and pyridostigmine bromide (Pyr-B) treatment, both trained and untrained. aVersus untrained SHR vehicle; bversus untrained SHR Pyr-B 5 mg; cversus untrained SHR Pyr-B 15 mg; dversus trained SHR vehicle; eversus trained SHR Pyr-B 5 mg. The figure was drawn in SigmaPlot 11.0 software (Systat Software Inc., San Jose, CA, USA; https://systatsoftware.com).