Figure 3

The effect of T-DXd on mRNA expression of CXCL9/10/11 in HER2-positive GC cells. (A, B) Dose- and time-dependent effect of T-DXd on mRNA expression of CXCL9, CXCL10, and CXCL11 in NCI-N87 cells (n = 3). (C) mRNA expression of CXCL9, CXCL10, and CXCL11 in NCI-N87 cells treated with 1 μg/ml human IgG, trastuzumab, or T-DXd (n = 3). Values are shown as means ± SEM. *P < 0.05, ***P < 0.001, ****P < 0.0001.