Figure 5
The effect of T-DXd on the expression of HLA class I in HER2-positive GC cells co-cultured with PBMC. (A) The expression of HLA class I in NCI-N87 cells co-cultured with or without PBMC in the absence or presence of 1 μg/ml T-DXd for 72 h (n = 3). Single culture, single culture of NCI-N87 cells; Co-PBMC, NCI-N87 cells co-cultured with PBMC. Representative histograms were shown. (B) IFN-γ production in supernatants of NCI-N87 co-cultured with or without PBMC in the absence or presence of T-DXd for 72 h (n = 3). Values are shown as means ± SEM. *P < 0.05, ***P < 0.001, ****P < 0.0001.
