Figure 5
The PamTps1 active site pocket. The overview of PamTps1 active site pocket from (A) top and (B) side views. Docking positions of (C) GPP and (D) FPP in PamTps1 active site cavity. The PamTps1 active site is a deep hydrophobic pocket consisting of C, D, F, G, H and J helices. The red–orange ball and stick chains represent the PPi of substrate, green spheres are the Mg2+, the orange side chains are the DTE motifs, the blue side chains are the hydrogen bond donor residues and the magenta side chains represent the aromatic residues.
