Figure 4
From: Effect of extracorporeal shock wave therapy on keratinocytes derived from human hypertrophic scars
Expression of proliferation/differentiation regulators in HTSKs. Significantly decreased mRNA levels of genes encoding p21 (CDKN1A) (A) and p27 (CDKN1B) (C) in HTSKs compared with those in HNKs. Significantly decreased protein levels of p21 (B) and p27 (D) in HTSKs compared with those in HNKs. NHKs and HTSKs were primary cultured from normal skin tissues and HTS tissues, respectively. In the fold change, HNKs marked as value 1; HNK, human normal keratinocyte; HTSK, hypertrophic scar keratinocyte; *P < 0.05 for HTSK vs. the corresponding matched HNK. Data represent means ± SD; n = 4 (HNK) and n = 4 (HTSK).
