Figure 5
From: Effect of extracorporeal shock wave therapy on keratinocytes derived from human hypertrophic scars
Expression of proliferation and activation marker in HTSKs after ESWT. Significantly decreased and increased mRNA (A) and protein levels (B) of keratin 14 (KRT14), a proliferation marker in HTSKs at 24 h or 72 h after ESWT under 0.2, and 0.3 mJ/mm2 of energy flux density, comparted with those in untreated control. Significantly increased and decreased mRNA (C) and protein levels (D) of keratin 6 (KRT6), an activation marker in HTSKs at 24 h or 72 h after ESWT under 0.1, 0.2, and 0.3 mJ/mm2 of energy flux density, comparted with those in untreated control. Significantly increased and unchanged mRNA (E) and protein levels (F) of keratin 17 (KRT17), anther activation marker in HTSKs at 24 h or 72 h after ESWT, comparted with those in untreated control. In the fold change, untreated control cells marked as value 1; Ct, untreated control cells; HTSK, hypertrophic scar keratinocyte; *P < 0.05 for ESWT-treated cells vs. the corresponding matched untreated control cells. Data represent means ± SD; n = 4.
