Figure 7
From: Effect of extracorporeal shock wave therapy on keratinocytes derived from human hypertrophic scars
Expression of apoptosis-related factors in HTSKs. Significantly increased and decreased mRNA levels of bax (BAX) (A) and bcl2 (BCL2) (C) in HTSKs at 24 h or 72 h after ESWT under 0.1, 0.2, and 0.3 mJ/mm2 of energy flux density, comparted with those in untreated control. Significantly increased and decreased protein levels of bax (B) and bcl2 (D) in HTSKs at 24 h or 72 h after ESWT, comparted with those in untreated control. Significantly increased mRNA (E) and protein levels (F) of ASK1 (MAP3K5) in HTSKs at 24 h or 72 h after ESWT, comparted with those in untreated control. Unchanged and significantly increased mRNA (G) and protein levels (H) of caspase 14 (CASP14) in HTSKs at 24 h or 72 h after ESWT, comparted with those in untreated control. In the fold change, untreated control cells marked as value 1; Ct, untreated control cells; HTSK, hypertrophic scar keratinocyte; *P < 0.05 for ESWT-treated cells vs. the corresponding matched untreated control cells. Data represent means ± SD; n = 4.
