Table 3 Impact of the effect of ESWT on human hypertrophic scar keratinocytes.
From: Effect of extracorporeal shock wave therapy on keratinocytes derived from human hypertrophic scars
Marker type | Protein and gene of interest | HTSKs compared to HNKs | After treatment 24 h | After treatment 72 h |
|---|---|---|---|---|
Proliferation | Keratin 5 (KRT5) | n.c | n.c | n.c |
Proliferation | Keratin 14 (KRT14) | n.c | − | + |
Activation | Keratin 16 (KRT6) | + | + | − |
Activation | Keratin 17(KRT17) | + | + | n.c |
Differentiation | Keratin 1 (KRT1) | + | − | + |
Differentiation | Keratin 10 (KRT10) | − | n.c | n.c |
Differentiation | Involucrin (IVL) | + | + | − |
Pro-apoptotic | Bax (BAX) | – – | + | − |
Anti-apoptotic | Bcl2 (BCL2) | + + | + | − |
Pro-apoptotic | Caspase 14 (CASP14) | – – | n.c | + |
Cell cycle regulator | p21 (CDKN1A) | + + | + | − |
Cell cycle regulator | p27 (CDKN1B) | + + | + | − |
