Table 1 Comparison of demographic and clinical features in the study groups.

From: Clinical efficacy and safety of tirofiban combined with conventional dual antiplatelet therapy in ACS patients undergoing PCI

 

Group L (N = 68)

Group M (N = 218)

Group H (N = 61)

F/χ2

P

Demographics

Age (years)

64.87 ± 10.41

65.52 ± 10.84

62.59 ± 8.19

1.927

0.147

Male, n (%)

52 (76.47)

179 (82.11)

54 (88.52)

3.184

0.204b

Smoker, n (%)

31 (45.59)

128 (58.72)

33 (54.10)

3.659

0.160b

Body-mass index (kg/m2)

25.52 ± 3.83

25.03 ± 3.36

24.50 ± 4.09

1.287

0.277

Duration time (hours)

52.85 ± 3.16

52.47 ± 3.67

52.32 ± 3.65

0.387

0.680

CYP2C19 gene

 Slow, n (%)

7 (10.29)

18 (8.26)

7 (11.48)

5.596

0.231b

 Middle, n (%)

30 (44.12)

67 (30.73)

20 (32.79)

  

 Rapid, n (%)

31 (45.59)

133 (61.01)

34 (55.74)

  

Medical history

Gastrointestinal bleeding, n (%)

0 (0)

6 (2.75)

2 (3.28)

1.922

0.349a

Hematencephalon, n (%)

0 (0)

2 (0.92)

0 (0)

0.645

1.000a

Hypertension, n (%)

37 (55.41)

124 (56.88)

31 (50.82)

0.737

0.692b

Hyperlipidemia, n (%)

22 (32.35)

76 (34.86)

24 (39.34)

0.712

0.700b

Diabetes mellitus, n (%)

23 (33.82)

71 (32.57)

11 (18.03)

5.281

0.071b

Atrial fibrillation, n (%)

47 (69.12)

141 (64.68)

49 (80.33)

5.417

0.067

Fibrinolytic therapy, n (%)

24 (35.29)

51 (23.39)

16 (26.23)

3.794

0.150

ACS classification

STEMI, n (%)

22 (32.35)

61 (27.98)

25 (40.98)

3.818

0.148

NSTEMI, n (%)

37 (54.41)

95 (43.58)

22 (36.07)

4.537

0.103

UA, n (%)

22 (32.35)

53 (24.31)

10 (16.39)

4.439

0.109

Infarct-related artery

Left main coronary artery, n (%)

10 (14.71)

37 (16.97)

4 (6.56)

4.124

0.127

Anterior descending, n (%)

40 (58.82)

126 (57.80)

31 (50.82)

2.098

0.925a

Circumflex artery, n (%)

9 (13.24)

30 (13.76)

6 (9.84)

2.031

0.732 a

Right coronary artery, n (%)

23 (33.82)

64 (29.36)

16 (26.23)

7.045

0.491a

Drug information

Dual antiplatelet (aspirin + clopidogrel), n (%)

65 (95.59)

206 (94.50)

57 (93.44)

0.287

0.866b

Oral anticoagulant, n (%)

47 (69.12)

141 (64.68)

49 (80.33)

5.417

0.067

Statin, n (%)

67 (98.53)

216 (99.08)

60 (98.36)

1.008

0.630a

ACEI/ARB, n (%)

54 (79.41)

170 (77.98)

52 (85.25)

1.546

0.462b

β-blocker, n (%)

62 (91.18)

191 (87.61)

54 (88.52)

0.645

0.724b

MACE, n (%)

1 (1.47)

1 (0.46)

0 (0)

1.580

0.606a

  1. a: fisher's precise test; b: chi-square; c: variance analysis.
  2. ACS acute coronary syndrome, STEMI acute ST-segment elevation myocardial infarction, NSTEMI non-acute ST-segment elevation myocardial infarction, UA unstable angina pectoris, ACEI angiotensin converting enzyme inhibitor, ARB angiotensin receptor blocker, MACE major adverse cardiovascular event.