Table 2 Variant of C10 C-terminal peptide. Apparent dissociation constant (Kapp) of C10-11 mAb for C10 peptide variants was calculated based on the fitting performed in the competition experiments (Fig. 1). The representativeness of the different sequences of the C10 peptide among Borrelia burgdorferi sl. is given in percentages. NB means no binding. BBss: Borrelia burgdorferi sensu stricto, Ba: Borrelia afzelii, Bg: B. garinii, Bbav: B. bavariensis.
C-terminal peptide | Kapp (nM) | Representativeness (%) | Example of B. burgdorferi s.l. strains |
|---|---|---|---|
1 : P V V A E S P K K P | 33 | 80.9 | Bbss B31; Bbss Bre13; Bbss ACA1; Bbss PLe; Bb PBo; Ba BO23; Ba PKo; Ba HT25; Bg PLi; Bg HB19; Bg PBes |
2 : P V V A E A P K K P | 146 | 0.9 | Bg PBr |
3 : P V V A E S P K K T | 60 | 0.9 | Bbss PWag |
4 : P V V A E S P K N P | NB | 0.9 | Bbss JD1, Ba K78 |
5 : P V V A E T P K K P | 179 | 5.5 | Bbav PBi |
6 : P V V A E N P K K P | NB | 0.9 | Bbss F045 |
7 : P V V A E S Q K K P | 170 | 0.9 | Ba BaC22 |
8 : P V V V E S P K K P | NB | 1.8 | Bbss ZS7 |
9 : P V M A E S P K K P | 125 | 0.9 | Bg 935 T |
10 : P I V A E S P K K P | 100 | 3.6 | Bbss N40; Bbss LDP74 |
11 : P I V A E S P K N P | NB | 2.7 | Bbss 297 |
