Figure 5

Expression of selected upregulated miRNAs in affected (XLHN) dogs and controls detected by small RNA-seq at each clinical time point (T1, T2, and T3). Expression of (a) miR-21, (b) miR-142, (c) miR-147 are shown. Data are presented as mean value ± standard deviation. The results from CPSS 2.0 analysis were used. (*: P-value < 0.05; **: P-value < 0.01; ***: P-value < 0.001; ****: P-value < 0.0001).