Figure 4 | Scientific Reports

Figure 4

From: Polyclonal alpaca antibodies protect against hantavirus pulmonary syndrome in a lethal Syrian hamster model

Figure 4

Gross lung pathology in Alp-PcIgG treated, ANDV infected hamsters. Syrian hamsters were infected with 154 FFU of Andes virus (ANDV) and lungs were collected upon euthanasia. Representative lung images for PBS treated hamsters as well as hamsters treated with anti-ANDV polyclonal alpaca IgG (Alp-PcIgG-ANDV) on days + 2/ + 4 and + 3/ + 5 with respect to challenge are shown. Note the diffuse deep red to plum colored appearance of the control (i.e. PBS) treated hamster lungs, indicating substantial inflammation and tissue damage. In comparison, lungs from the Alp-PcIgG treated hamsters appear a healthy pinkish color with rare areas of deeper red.

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