Table 4 Comparison of predicted pathways by IPA in current study with other studies that investigated the response to NDV infection.
zPathways | z-Score (current study) | IPA prediction in other studies using non-virulent NDV | |
|---|---|---|---|
Inhibition | Activation | ||
TNFR2 signalling | − 3.00 | Spleen21 | Trachea18 |
TNFR1 signalling | − 2.32 | Spleen21 | Trachea18 |
GP6 signalling pathway | − 2.23 | Spleen21 | Harderian gland19 |
Leukocyte extravasation signalling | − 2.21 | Spleen21 | Trachea18 |
Production of nitric oxide and reactive oxygen species in macrophages | − 2.02 | Spleen21 | Trachea18 |
Fcγ receptor-mediated phagocytosis in macrophages and monocytes | − 1.54 | Spleen21 | Trachea18 |
Tec kinase signalling | − 1.50 | Spleen21 | |
B cell receptor signalling | − 1.13 | Spleen21 | trachea18 |
Integrin signalling | − 0.92 | Spleen21 | Lung17 |
IL-8 signalling | − 0.53 | Spleen21 | |
CD40 signalling | − 0.42 | Spleen21 | Trachea18 |
Thrombin signalling | − 0.12 | Spleen21 | Lung17 |
IL-6 signalling | 0.18 | Spleen21 | Trachea18 |
P2γ purigenic receptor signalling pathway | 0.88 | Spleen21 | Lung17 |
Relaxin signalling | 1.00 | Spleen21 | Lung17 |
Ephrin receptor signalling | 1.76 | Spleen21 | Lung17 |
