Table 3 Top significant biological processes identified by RNA sequencing analysis of human VAT.
From: The human type 2 diabetes-specific visceral adipose tissue proteome and transcriptome in obesity
Pruning typea | None | Elim | Weight | ||||
|---|---|---|---|---|---|---|---|
Biological process GO term | p-value | p-value (FDR) | p-value (Bonferroni) | Biological process GO term | p-value | Biological process GO term | p-value |
Immune response | 1.00E−24 | 1.00E−24 | 1.00E−24 | Neutrophil degranulation | 1.80E−19 | Neutrophil degranulation | 1.00E−20 |
Immune system process | 1.00E−24 | 1.00E−24 | 1.00E−24 | Inflammatory response | 2.80E−12 | Inflammatory response | 3.40E−16 |
Defense response | 1.00E−24 | 1.00E−24 | 1.00E−24 | Regulation of complement activation | 1.00E−10 | Regulation of complement activation | 2.10E−13 |
Positive regulation of immune system process | 1.00E−24 | 1.00E−24 | 1.00E−24 | Positive regulation of neutrophil chemotaxis | 2.40E−09 | Cytokine-mediated signaling pathway | 1.90E−12 |
Inflammatory response | 1.00E−24 | 1.00E−24 | 1.00E−24 | Innate immune response | 5.20E−09 | B-cell receptor signaling pathway | 7.40E−12 |
