Figure 6
From: Analysis of the signal cross talk via CCL26 in the tumor microenvironment in osteosarcoma
Changes in the lung nodules and the expression of Rac and phosphorylated Src in pulmonary metastatic lesions. (A) The group given anti-CCL26 Ab showed a significant suppression of the size of the pulmonary metastatic lesion. (B) Immunostaining of the tissues collected from the pulmonary metastatic lesion. Decreased expression of Rac and p-Src was observed in the group administered anti-CCL26 Ab. Original magnification, × 400; Scale bars: 50 μm. (C) The number of Rac and p-Src positive cells per unit area. Data represents represent the mean ± SD of three independent experiments. p < 0.05 was considered to indicate significance: (*) p < 0.05, (**) p < 0.01.
