Table 2 Mouse strain information.
Common name | Strain name/standardized nomeclature | Repeat length/allele type | Gene characteristics | Provider |
|---|---|---|---|---|
zQ175DN | B6J.129S1-Htttm1.1Mtc/190ChdiJ | 180–220 CAG/knock-in | Endogenous murine Htt gene, chimeric human/mouse exon 1 | CHDI |
R6/2 | B6CBA-Tg(HDexon1)62Gpb/125JChdi | 128 CAG/Tg fragment | HTT promoter, exon 1 of human HTT | CHDI |
PcP2-82Q | 82 CAG/Tg | Human ataxin-1 gene with expanded CAG under control of the purkinje cell-specific PcP2 promoter | Dr. Harry Orr (University of Minnesota) | |
SCA154Q/2Q | 154 CAG/knock-in | Endogenous murine Sca1 locus | Dr. Huda Zoghbi (Baylor College of Medicine) |
