Figure 6
From: Amine modification of calcium phosphate by low-pressure plasma for bone regeneration
In vivo experiments on the new bone formation inside porous β-TCP disks. (A) Schematic diagram of the in vivo implantation of porous β-TCP disks and post-operative evaluations (drawn by using Microsoft PowerPoint 2016). (B) Micro-CT analysis of new bone volumes formed inside the untreated (open circles) and plasma-treated (filled squares) porous β-TCP disks at postoperative 3 and 6 weeks. (C) The 3D reconstruction of the calvarial bone implanted with untreated (left) and plasma-treated (right) porous β-TCP disks at postoperative 6 weeks. The gray grain-like structures indicate newly formed bone, and the white plate or slab-like structure with two circular holes represents the rat calvarial bone. The β-TCP disks are not depicted and therefore the volume occupied by β-TCP is represented by void space (black) in this image. (D) Micro-CT analysis of residual β-TCP volumes of the untreated (open circles) and plasma-treated (filled squares) porous β-TCP disks at postoperative 3 and 6 weeks. The data in B and D are expressed as mean ± SD (n = 5 for 3 weeks, n = 15 for 6 weeks). **p < 0.01, ****p < 0.0001. Wilcoxon matched-pairs signed-rank test.
